alexa Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers.


Journal of Food Processing & Technology

Author(s): Kamaratos AV, Tzirogiannis KN, Iraklianou SA, Panoutsopoulos GI, Kanellos IE,

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Abstract In this study, we investigate the effect of manuka honey-impregnated dressings (MHID) on the healing of neuropathic diabetic foot ulcers (NDFU). A total of 63 Caucasians, type 2 diabetic patients followed up in the diabetic foot outpatient clinic comprised the study population. Patients were randomised in two groups as follows: group I patients were treated with MHID and group II patients were treated with conventional dressings (CD). The patients were followed up on a weekly basis for 16 weeks. Mean healing time was 31 ± 4 days in group I versus 43 ± 3 days in group II (P < 0·05). In group I patients 78·13\% of ulcers became sterile during the first week versus 35·5\% in group II patients; the corresponding percentages for weeks 2, 4 and 6 were 15·62\% versus 38·7\%, 6·25\% versus 12·9\% and 0\% versus 12·9\% respectively. The percent of ulcers healed did not differ significantly between groups (97\% for MHID and 90\% for CD). MHID represent an effective treatment for NDFU leading to a significant reduction in the time of healing and rapid disinfection of ulcers. © 2012 The Authors. International Wound Journal © 2012 Inc and John Wiley & Sons Ltd. This article was published in Int Wound J and referenced in Journal of Food Processing & Technology

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