alexa Mature mediastinal teratoma and sarcoid-like granulomatosis


Occupational Medicine & Health Affairs

Author(s): Gary L Rustom, PL Declercq, L Veresezan, JF Muir, A Cuvelier

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Introduction: Sarcoidosis is a systemic granulomatous disease. However when epithelioid and giant cell granulomas are identified in the vicinity of a neoplastic disease, they can match a sarcoid reaction.

Observation: We report the case of a young woman in whom granulomas noncaseating were identified at mediastinal lymphadenopathy. It also had a large anterior mediastinal lesion excision which has revealed a mature teratoma intrathymique.

Conclusion: The association between granulomatous sarcoid-like and some cases of testicular germ cell tumors has been described in the literature. Our case corresponds to a secondary sarcoid reaction to the teratoma. Mediastinal lymph node granulomas could be the result of a hypersensitivity reaction in response to antigens by salted teratoma.

This article was published in Revue des Maladies Respiratoires and referenced in Occupational Medicine & Health Affairs

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