Author(s): Gary L Rustom, PL Declercq, L Veresezan, JF Muir, A Cuvelier
Introduction: Sarcoidosis is a systemic granulomatous disease. However when epithelioid and giant cell granulomas are identified in the vicinity of a neoplastic disease, they can match a sarcoid reaction.
Observation: We report the case of a young woman in whom granulomas noncaseating were identified at mediastinal lymphadenopathy. It also had a large anterior mediastinal lesion excision which has revealed a mature teratoma intrathymique.
Conclusion: The association between granulomatous sarcoid-like and some cases of testicular germ cell tumors has been described in the literature. Our case corresponds to a secondary sarcoid reaction to the teratoma. Mediastinal lymph node granulomas could be the result of a hypersensitivity reaction in response to antigens by salted teratoma.Occupational Medicine & Health Affairs