alexa [Mature mediastinal teratoma and sarcoid-like granulomatosis].


Occupational Medicine & Health Affairs

Author(s): GaryRustom L, Declercq PL, Veresezan L, Muir JF, Cuvelier A

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Abstract INTRODUCTION: Sarcoidosis is a systemic granulomatous disorder. However, when epithelioid cell granulomata are found in association with malignancy, they could correspond to a sarcoid reaction. CASE REPORT: We report the case of a young woman with mediastinal lymphadenopathy containing non-caseating granulomata. She also had a mass in the anterior mediastinum which proved, on surgical resection, to be an intrathymic mature teratoma. CONCLUSION: An association between a sarcoid-like reaction and testicular germ cell tumours has been described in literature. Our observation of a sarcoid reaction associated with a teratoma could be due to a hypersensitivity reaction to antigen released by the tumour. Copyright © 2012 SPLF. Published by Elsevier Masson SAS. All rights reserved. This article was published in Rev Mal Respir and referenced in Occupational Medicine & Health Affairs

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