alexa Mechanism of action of cathinone: the active ingredient of khat (Catha edulis).
Psychiatry

Psychiatry

Journal of Addiction Research & Therapy

Author(s): Patel NB

Abstract Share this page

Abstract OBJECTIVE: To review the current understanding of the mechanism of action of cathinone, the active ingredient of khat. DATA SOURCE: Published experimental studies on the nature and action and effect of cathinone on the central nervous system both in animals and humans. DATA EXTRACTION: Data was taken from work published on the mechanism of action of cathinone and also from work where the action of cathinone and amphetamine was compared. DATA SYNTHESIS: Data from various studies on cathinone was compared for common themes with regards to its action and similarity with the known mechanism of action of amphetamine. CONCLUSION: The experimental work shows that cathinone is a liable substance, structually related to amphetamine, and similarly to amphetamine, increases the levels of dopamine in the brain by acting on the cathecholaminergic synaspes. Hence the psychostimulant effect of khat can be accounted for by the mechanism of cathinone, which is considered to be its main active ingredient.
This article was published in East Afr Med J and referenced in Journal of Addiction Research & Therapy

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords