Author(s): Fielding CJ, Fielding PE
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Abstract The plasma membrane of mammalian cells consists of microdomains differing in lipid and protein composition. Two distinct classes of cholesterol/sphingolipid microdomain (caveolae and lipid rafts) are assembly points for transmembrane signalling complexes. Recent evidence suggests that transient changes in cholesterol content may be important in regulating signal transduction.
This article was published in Biochem Soc Trans
and referenced in Journal of Cytology & Histology