alexa Meta-analysis of psychological interventions to promote adherence to treatment in pediatric chronic health conditions.


Journal of Blood Disorders & Transfusion

Author(s): Kahana S, Drotar D, Frazier T

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Abstract OBJECTIVE: To estimate the effectiveness of adherence-promoting psychological interventions for pediatric populations with chronic health conditions. METHODS: A meta-analysis was conducted on 70 adherence-promoting psychological intervention studies among chronically ill youth using a weighted least squares approach and random effect model. RESULTS: Medium effects sizes were found for the behavioral (mean d =.54, 95\% confidence interval [CI] = 0.34-0.73, n = 10) and multi-component interventions (mean d =.51, 95\% CI = 0.45-0.57, n = 46), while educational interventions displayed a small effect size with adherence (mean d =.16, 95\% CI = 0.10-0.22, n = 23). Study designs incorporating pre-post comparisons yielded effect sizes approaching the medium range (mean d =.42, 95\% CI = 0.36-0.48, n = 30). CONCLUSIONS: Behavioral and multi-component interventions appear to be relatively potent in promoting adherence among chronically ill youth. Recommendations for future research and methodological issues are presented. This article was published in J Pediatr Psychol and referenced in Journal of Blood Disorders & Transfusion

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