Author(s): MartinezOutschoorn UE, Sotgia F, Lisanti MP, MartinezOutschoorn UE, Sotgia F, Lisanti MP
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Abstract Profound metabolic differences between cancer cells and fibroblasts promote tumorigenesis. A study by Valencia and colleagues in this issue of Cancer Cell supports this assertion. They observed that metabolic asymmetry in prostate tumors drives aggressive disease with high p62 in anabolic cancer cells, but loss of p62 in catabolic fibroblasts. Copyright © 2014 Elsevier Inc. All rights reserved.
This article was published in Cancer Cell
and referenced in Journal of Thyroid Disorders & Therapy