alexa Metastasis to bone: causes, consequences and therapeutic opportunities.


Journal of Orthopedic Oncology

Author(s): Mundy GR, Mundy GR

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Abstract The most common human cancers --lung, breast and prostate -- have a great avidity for bone, leading to painful and untreatable consequences. What makes some cancers, but not others, metastasize to bone, and how do they alter its physiology? Some of the molecular mechanisms that are responsible have recently been identified, and provide new molecular targets for drug development. This article was published in Nat Rev Cancer and referenced in Journal of Orthopedic Oncology

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