alexa Metastatic carcinoid tumors--are we making the cut?


Archives of Surgical Oncology

Author(s): Coan KE, Gray RJ, Schlinkert RT, Pockaj BA, Wasif N

Abstract Share this page

Abstract BACKGROUND: Although controversial, surgical resection for metastatic carcinoid tumors (MCTs) can potentially prolong survival. METHODS: Patients with MCTs were identified from the Surveillance, Epidemiology and End Results database. Patients undergoing surgery were compared to unresected patients. RESULTS: Surgery was performed in 33\% of patients. Predictors of surgery included age <50 years (odds ratio [OR], 2.4), low grade (OR, 3.1), and the appendix (OR, 36.2) or small intestine (OR, 27.2) as the primary site. Predictors of adverse survival included high grade (hazard ratio, 2.4) and no surgery (hazard ratio, 2.5) or surgery on only primary or distant disease (hazard ratio, 1.5) compared with surgery for both. Survival at 5 years was 5\% with no surgery, 28\% with surgery on either site, and 46\% with surgery at both sites (P < .001). CONCLUSIONS: Surgery for MCTs is more common in younger patients, those with low-grade disease, and those with small bowel or appendiceal primary tumors. Although selection bias cannot be excluded, these data lend support to "debulking" for MCT. Copyright © 2013 Elsevier Inc. All rights reserved. This article was published in Am J Surg and referenced in Archives of Surgical Oncology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version