alexa MicroRNAs: target recognition and regulatory functions.
Genetics

Genetics

Molecular Biology: Open Access

Author(s): Bartel DP, Bartel DP

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Abstract MicroRNAs (miRNAs) are endogenous approximately 23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their posttranscriptional repression. This review outlines the current understanding of miRNA target recognition in animals and discusses the widespread impact of miRNAs on both the expression and evolution of protein-coding genes.
This article was published in Cell and referenced in Molecular Biology: Open Access

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