Author(s): Singh KK, Tsai LH
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Abstract The microtubule network is crucial for the developing nervous system, and mutations in tubulin-encoding genes disrupt neuronal migration. Tischfield et al. (2010) now report that mutations in the tubulin-encoding gene TUBB3 have a striking impact on microtubule dynamics in neurons, resulting in a diverse set of disease symptoms.
This article was published in Cell
and referenced in Journal of Neurology & Neurophysiology