alexa Minimizing surgical-site infections


Clinical Microbiology: Open Access

Author(s): Richard P Wenzel

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This article has no abstract; the first 100 words appear below.

Primitive ancestors of Homo sapiens and their colonizing bacteria have coevolved for approximately 500,000 years; some experts estimate that the total number of human cells is 1013 and the total number of colonizing microbes is 1014. Despite this 10-to-1 inequity, the balance of power is influenced by an intact human immune system and the integrity of the skin and mucous membranes. Operative procedures disrupt this balance, resulting in a risk of surgical-site infections from endogenous flora, including colonizing strains of Staphylococcus aureus. Each year in the United States, more than 30 million operative procedures are performed. The risk

This article was published in N Engl J Med and referenced in Clinical Microbiology: Open Access

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