alexa Modeling protein complexes with BiGGER.
Molecular Biology

Molecular Biology

Journal of Cell Science & Therapy

Author(s): Krippahl L, Moura JJ, Palma PN

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Abstract This article describes the method and results of our participation in the Critical Assessment of PRediction of Interactions (CAPRI) experiment, using the protein docking program BiGGER (Bimolecular complex Generation with Global Evaluation and Ranking) (Palma et al., Proteins 2000;39:372-384). Of five target complexes (CAPRI targets 2, 4, 5, 6, and 7), only one was successfully predicted (target 6), but BiGGER generated reasonable models for targets 4, 5, and 7, which could have been identified if additional biochemical information had been available. Copyright 2003 Wiley-Liss, Inc. This article was published in Proteins and referenced in Journal of Cell Science & Therapy

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