alexa Modulatory effects of Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in mice.
Agri and Aquaculture

Agri and Aquaculture

Journal of Aquaculture Research & Development

Author(s): Nair SC, Salomi MJ, Panikkar B, Panikkar KR

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Abstract In mice, an extract of Crocus sativus stigmas partially prevented the decreases in body weight, hemoglobin levels and leucocyte counts caused by 2 mg/kg of cisplatin i.p. for 5 days. Treatment with the C. sativus extract also significantly prolonged the life span of cisplatin-treated mice almost three-fold. In contrast, an extract of Nigella sativa seed only tended to protect from cisplatin-induced falls in hemoglobin levels and leucocyte counts.
This article was published in J Ethnopharmacol and referenced in Journal of Aquaculture Research & Development

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