alexa Molecular eco-systems biology: towards an understanding of community function.
General Science

General Science

Journal of Biotechnology & Biomaterials

Author(s): Raes J, Bork P

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Abstract Systems-biology approaches, which are driven by genome sequencing and high-throughput functional genomics data, are revolutionizing single-cell-organism biology. With the advent of various high-throughput techniques that aim to characterize complete microbial ecosystems (metagenomics, meta-transcriptomics and meta-metabolomics), we propose that the time is ripe to consider molecular systems biology at the ecosystem level (eco-systems biology). Here, we discuss the necessary data types that are required to unite molecular microbiology and ecology to develop an understanding of community function and discuss the potential shortcomings of these approaches. This article was published in Nat Rev Microbiol and referenced in Journal of Biotechnology & Biomaterials

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