alexa Mood disorders in opioid-dependent patients.


Journal of Psychiatry

Author(s): Ahmadi J, Majdi B, Mahdavi S, Mohagheghzadeh M, Ahmadi J, Majdi B, Mahdavi S, Mohagheghzadeh M

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Abstract AIMS: To assess the rate of current mood disorders in opioid-dependent outpatients. DESIGN: Prevalence study of DSM-IV mood disorders. SETTINGS: Private and government clinics. PARTICIPANTS: Five hundred unpaid opioid-dependent patients who had voluntarily sought treatment. MEASUREMENTS: The Research version of structured clinical interview for DSM-IV Axis I Disorders (SCID-I). RESULTS: The mean age of the subjects (487 men and 13 women) was 33.4 years, ranging from 16 to 67. The majority (68.2\%) had private sector job and 13.4\% were unemployed. The majority (59.8\%) had education at the level of primary, guidance or high school and only 3.8\% were illiterate. Three hundred and thirty six (67.2\%) subjects were diagnosed as having mood disorders. Of the subjects 274 (54.8\%) had substance induced depression, 37 (7.4\%) major depression, 14 (2.8\%) dysthymia, five (1\%) depression due to general medical condition, three (0.6\%) cylothymia, three (0.6\%) bipolar mood disorder type I. None was diagnosed as having bipolar mood disorder type II. Of the participants 319 (63.8\%) reported more than 5 years use of opioid. Of the subjects only 16 (3.2\%) reported no episode of abstinence and the majority 484 (96.8\%) reported one or more episodes of abstinences. About 4.2\% (21) reported less than 1 g/day and the majority 86.4\% (432) reported between 1 and 5 g/day current use of opioid. CONCLUSION: Due to high rates of mood disorders in opioid-dependent subjects, psychiatric services should be open and accessible to the patients, especially those who voluntarily seek help and treatment. This article was published in J Affect Disord and referenced in Journal of Psychiatry

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