alexa Multiple regulators of ultrasonic vocalization in the infant rat.
Neurology

Neurology

Autism-Open Access

Author(s): Hofer MA

Abstract Share this page

Abstract This paper reviews our growing understanding of the external environmental and the internal neuroregulatory mechanisms for the infant rat's vocal response to abrupt isolation from nest, littermates and mother. Interactions of the rat pup with specific components of its animate and inanimate environment have been identified and found to exert a tonic regulatory action on the neural systems mediating ultrasonic vocalization (USV). In isolation, withdrawal of these regulators produces an acute outburst of calling. Changes in rate of ultrasonic calling in response to administration of receptor agonist and antagonist agents generally correspond to the effects of those agents on measures of anxiety in adult animals and in human clinical populations, suggesting a conservation of neural substrates for anxiety in evolution and in development. The inhibition of isolation calling in response to predator cues and its potentiation by brief exposure to maternal cues, represent novel forms of regulation with implications for neuroendocrine development and for the neurobiology of early cognitive-emotional processes.
This article was published in Psychoneuroendocrinology and referenced in Autism-Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • 3rd International Conference on Autism
    Aug 21-22, 2017 Los Angeles, USA
  • 3rd International Conference on Epilepsy and Treatment
    September 01-17 Brussels, Belgium

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords