alexa Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters.
Materials Science

Materials Science

Journal of Nanomedicine & Nanotechnology

Author(s): Maiti KK, Samanta A, Vendrell M, Soh KS, Olivo M,

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Abstract SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters. This article was published in Chem Commun (Camb) and referenced in Journal of Nanomedicine & Nanotechnology

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