alexa N-acetylcysteine for preventing acute kidney injury in cardiac surgery patients with pre-existing moderate renal insufficiency.


Journal of Clinical & Experimental Cardiology

Author(s): Wijeysundera DN, Beattie WS, Rao V, Granton JT, Chan CT

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Abstract PURPOSE: N-acetylcysteine may prevent acute kidney injury after cardiac surgery. To determine if N-acetylcysteine warrants definitive evaluation in a large multicentre trial, we evaluated its effects on a surrogate outcome, estimated glomerular filtration rate (eGFR), in a randomized trial. METHODS: One-hundred-seventy-seven cardiac surgery patients with moderate pre-existing renal insufficiency (eGFR
  • DOI: 10.1007/BF03026790
  • This article was published in Can J Anaesth and referenced in Journal of Clinical & Experimental Cardiology

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