alexa Nail discoloration due to tinzaparin sodium.


Journal of Pigmentary Disorders

Author(s): Takci Z, Ozoguz P, Takci Z, Ozoguz P

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Abstract Tinzaparin sodium is a low molecular weight heparin formed by the enzymatic degradation of porcine unfractionated heparin, and is effective in the prevention and treatment of thromboembolic disease. We report a 31-year-old female patient with a history of recurrent pregnancy loss due to thrombophilia, who developed nail discoloration after 8 weeks of tinzaparin sodium therapy. No other pigmentation was found elsewhere on the skin, mucous membranes, teeth, or sclerae. To our knowledge, nail pigmentation following tinzaparin sodium therapy is an unknown side effect and has not been reported previously in the English literature. This article was published in Cutan Ocul Toxicol and referenced in Journal of Pigmentary Disorders

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