alexa National General Practice Study of Epilepsy: recurrence after a first seizure.


International Journal of Neurorehabilitation

Author(s): Hart YM, Sander JW, Johnson AL, Shorvon SD

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Abstract In the National General Practice Study of Epilepsy 564 patients classified as having definite seizures have been followed up for 2-4 years. 67\% (95\% confidence interval 63-71\%) had a recurrence within 12 months of the first seizure, and 78\% (74-81\%) had a recurrence within 36 months. Seizures associated with a neurological deficit presumed present at birth had a high rate of recurrence (100\% by 12 months), whereas seizures that occurred within 3 months of an acute insult to the brain, such as head injury or stroke, or in the context of an acute precipitant such as alcohol, carried a much lower risk of recurrence (40\% [29-51\%] by 12 months). Other factors affecting the risk of recurrence were age-the highest risk being for patients under the age of 16 (83\% [77-89\%] by 36 months) or over the age of 59 (83\% [76-90\%] by 36 months-and type of first seizure-the risk of recurrence being much higher for patients with simple partial or complex partial seizures (94\% [90-99\%] by 36 months) than for those with generalised tonic clonic seizures (72\% [67-77\%] by 36 months).
This article was published in Lancet and referenced in International Journal of Neurorehabilitation

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