alexa Natural course of epilepsy concomitant with CNS tuberculomas.
Clinical Research

Clinical Research

Journal of Clinical Case Reports

Author(s): AlSemari A, Baz S, Alrabiah F, AlKhairallah T, Qadi N,

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Abstract BACKGROUND: Epilepsy is relatively common in CNS tuberculomas, but its natural course is unclear. AIM: To determine the prevalence and prognosis of epilepsy in patients with seizures related to CNS tuberculomas. METHODS: We retrospectively reviewed the charts of patients with CNS tuberculomas who presented at our institution between 1983 and 2001. RESULTS: Seizures occurred in 22 of 93 (23.6\%) of the patients with CNS tuberculomas. These patients were treated with standard antituberculous therapy for a period varying between 6 and 20 months. Sixty-three out of 93 patients were cured of tuberculosis, and 21 of the 63 (33\%) who had concomitant epilepsy became seizure-free. TB recurred in 3 patients, and 1 out of 22 who had concomitant epilepsy continued to have seizures; 3 died and 24 were lost to follow-up. Anti-epileptic medications were discontinued after completion of the anti-TB course. CONCLUSION: Seizures are commonly associated with CNS tuberculomas and most often resolve after successful treatment of the underlying CNS tuberculosis. Copyright © 2011 Elsevier B.V. All rights reserved. This article was published in Epilepsy Res and referenced in Journal of Clinical Case Reports

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