Author(s): Feiz V, Oberg TJ, Kurz CJ, Mamalis N, Moshirfar M
Abstract Share this page
Abstract PURPOSE: We are reporting a case of bilateral corneal melt after photorefractive keratectomy requiring bilateral corneal transplantations. RESULTS: A 35-year-old man underwent uncomplicated photorefractive keratectomy and was treated postoperatively with topical nepafenac, one drop in both eyes every 2 hours. Three days into this course of treatment, the patient developed bilateral irritation and the dose was decreased to one drop every 4 hours. The next day, he developed stromal melting in both eyes. Although nepafenac was discontinued at this point, the ulcerative keratolysis progressed in both eyes requiring penetrating keratoplasty. CONCLUSIONS: We report a case of sterile ulceration after photorefractive keratectomy surgery, which we believe was caused by frequent postoperative dosing of nepafenac.
This article was published in Cornea
and referenced in Journal of Clinical & Experimental Ophthalmology