Author(s): Schwartz MA, Ginsberg MH
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Abstract Multicellular organisms must coordinate signals from adhesion receptors with those from other signalling receptors (for example, growth factor receptors). Here, we briefly review paradigms of integrin-adhesion-receptor signalling. We discuss how adhesive signalling is coordinately regulated through intersecting networks. We also examine some examples of how some forms of integrin crosstalk may lead to unforeseen and potentially deleterious responses.
This article was published in Nat Cell Biol
and referenced in Journal of Biomimetics Biomaterials and Tissue Engineering