alexa Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship.


Journal of Glycobiology

Author(s): Kaneko M, Yamada K, Miyamoto T, Inagaki M, Higuchi R

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Abstract The effects of the gangliosides isolated from echinoderms on the neuritogenesis of a rat pheochromocytoma cell line (PC-12 cells) in the presence of nerve growth factor were investigated. The results show that they displayed neuritogenic activity. Based on the observed results, a structure-activity relationship has been established.
This article was published in Chem Pharm Bull (Tokyo) and referenced in Journal of Glycobiology

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