Author(s): Arimura N, Kaibuchi K, Arimura N, Kaibuchi K
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Abstract After they are born and differentiate, neurons break their previous symmetry, dramatically change their shape, and establish two structurally and functionally distinct compartments - axons and dendrites - within one cell. How do neurons develop their morphologically and molecularly distinct compartments? Recent studies have implicated several signalling pathways evoked by extracellular signals as having essential roles in a number of aspects of neuronal polarization.
This article was published in Nat Rev Neurosci
and referenced in Journal of Alzheimers Disease & Parkinsonism