alexa New bioactive secondary metabolites from Bornean red alga, Laurencia similis (Ceramiales).
Psychiatry

Psychiatry

Journal of Addiction Research & Therapy

Author(s): Kamada T, Vairappan CS

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Abstract A Bomean red algal population of Laurencia similis Nam et Saito was analyzed for its secondary metabolite composition. Seven compounds were identified: ent-1(10)-aristolen-9beta-ol (1), (+)-aristolone (2), axinysone B (3), 9-aristolen-1alpha-ol (4), 2,3,5,6-tetrabromoindole (5), 1-methyl-2,3,5,6-tetrabromoindole (6), and 1-methyl-2,3,5-tribromoindole (7). Compound 1 was identified as a new optical isomer of 1(10)-aristolen-9beta-ol. Compounds 1, 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines.
This article was published in Nat Prod Commun and referenced in Journal of Addiction Research & Therapy

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