Author(s): Rizzo R, Bortolotti D, Baricordi OR, Fainardi E
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Abstract Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule with an important role at the fetus-maternal interface, preventing fetus recognition and abortion. The role of HLA-G as an immune-modulatory and anti-inflammatory molecule has led to investigate its role in pathological conditions. In these years, HLA-G has been shown to have an important implication in inflammatory pathologies. The focus of this review is to up-date the scientific knowledge on the expression of HLA-G molecules in inflammatory conditions.
This article was published in Inflamm Allergy Drug Targets
and referenced in Journal of Transplantation Technologies & Research