Author(s): HerreroGonzalez S, Di Cristofano A
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Abstract Cheung and colleagues identify PIK3R1 and PIK3R2, the genes encoding the α and β isoforms of the phosphatidylinositol 3-kinase (PI3K) p85 regulatory subunit, as additional mutation targets in endometrial cancer, and describe a novel mechanism leading to PTEN loss.
This article was published in Cancer Discov
and referenced in Journal of Integrative Oncology