alexa New routes to old places: PIK3R1 and PIK3R2 join PIK3CA and PTEN as endometrial cancer genes.


Journal of Integrative Oncology

Author(s): HerreroGonzalez S, Di Cristofano A

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Abstract Cheung and colleagues identify PIK3R1 and PIK3R2, the genes encoding the α and β isoforms of the phosphatidylinositol 3-kinase (PI3K) p85 regulatory subunit, as additional mutation targets in endometrial cancer, and describe a novel mechanism leading to PTEN loss. This article was published in Cancer Discov and referenced in Journal of Integrative Oncology

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