alexa Nitrogen-fixing aerobic bacteria have higher genomic GC content than non-fixing species within the same genus.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Data Mining in Genomics & Proteomics

Author(s): McEwan CE, Gatherer D, McEwan NR, McEwan CE, Gatherer D, McEwan NR, McEwan CE, Gatherer D, McEwan NR

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Abstract The genomic GC contents of both nitrogen-fixing and non-fixing members of eight genera of bacteria are investigated. Analysis by t-tests showed that in the two aerobic general investigated (Aquaspirillum and Vibrio) there is a significantly higher GC content in the nitrogen-fixing members of the genus than in those unable to fix nitrogen, whilst in aerobic genera there is either no GC bias, or in the case of two genera (Rhodospirillum and Clostridium) there is a significantly higher GC content in the non-fixing organisms. This suggests that, in many genera, directional mutational pressures are different in nitrogen-fixing and non-fixing organisms. These results are discussed in the light of known mechanisms of mutation pressure and their relation to environmental variables.
This article was published in Hereditas and referenced in Journal of Data Mining in Genomics & Proteomics

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