Author(s): Prakash AO, Tewari RK, Mathur R, Prakash AO, Tewari RK, Mathur R
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Abstract Neem oil, a natural product of Azadirachta indica was investigated for various hormonal properties in relation to its post-coital contraceptive action. At subcutaneous doses up to 0.3 ml/rat, neem oil did not possess any estrogenic, anti-estrogenic or progestational activity and appeared not to interfere with the action of progesterone. These findings were confirmed using the histo-architecture of the uterus of treated rats. Since the post-coital contraceptive effect of neem oil seems to be non-hormonal, neem oil would be expected to elicit less side effects than the steroidal contraceptives.
This article was published in J Ethnopharmacol
and referenced in Journal of Diabetic Complications & Medicine