alexa Nonruptured abdominal aortic aneurysm: six-year follow-up results from the multicenter prospective Canadian aneurysm study. Canadian Society for Vascular Surgery Aneurysm Study Group


Angiology: Open Access

Author(s): Johnston KW

Abstract Share this page



Based on the prospective analysis of data on 680 patients undergoing surgery for nonruptured abdominal aortic aneurysm (AAA) and recorded in the Canadian Society for Vascular Surgery Aneurysm Registry, this study determines the late survival rate by comparison to an age- and sex-matched population, the causes of late death, the effect of heart-related death on late survival, and the prognostic variables that are associated with late survival.


To identify the variables that were associated with survival, statistical methods included Kaplan-Meier analysis and Cox regression analysis. The Canadian Society for Vascular Surgery Aneurysm Registry provided ongoing current follow-up of patients.


The survival rate was 94.6% at 1 month, 90.7% at 1 year, 87.1% at 2 years, 81.0% at 3 years, 74.0% at 4 years, 67.7% at 5 years, and 60.2% at 6 years. The late survival rate of patients with AAA is significantly less than the age- and sex-matched normal population (60.2% versus 79.2%). In the AAA group, heart-related causes of late death (44.4% versus 34.1%) and cerebrovascular causes (8.3% versus 5.8%) were more frequent. The calculated 5-year heart-related mortality rate is 14.3%. This is higher than the heart-related mortality rate for the age- and sex-matched population, which is 6.4%. Hence, the risk of heart-related death for patients who have undergone AAA repair is increased by 1.6% per year. Vascular complications from aortic aneurysm repair or recurrent aneurysmal disease were an uncommon cause of late death: ruptured thoracic aneurysm, 1.5%; ruptured aortic false aneurysm, 1.5%; and aortoenteric fistula, 0%. This incidence appears to be less than reported in earlier series. By Cox regression analysis, the variables that were significant predictors of a lower late survival rate were increased age, preoperative electrocardiogram indicating a previous myocardial infarction, and elevated serum creatinine levels.


Because cardiac complications accounted for 68.8% (22/32) of the 4.7% in-hospital mortality rate (i.e., a heart-related mortality rate of 3.2%), it seems reasonable to develop a strategy to reduce the cardiac operative risk by identifying and treating patients at high risk before operation. However, it is doubtful that a preoperative program that screens and treats all patients can be cost-effective in preventing late heart-related deaths.

  • To read the full article Visit
  • Open Access
This article was published in J Vasc Surg and referenced in Angiology: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version