alexa Nosocomial infections and risk factors in the intensive care unit of a teaching and research hospital: a prospective cohort study.
Medicine

Medicine

Emergency Medicine: Open Access

Author(s): Ak O, Batirel A, Ozer S, olakolu S

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Abstract BACKGROUND: To evaluate the incidence, risk factors and etiology of nosocomial infections (NIs) in the intensive care unit (ICU) of our hospital in order to improve our infection control policies. MATERIAL/METHODS: A 1-year prospective cohort study of nosocomial infection (NI) surveillance was conducted in our ICU in 2008. RESULTS: Out of 1134 patients hospitalized in the ICU for a period of 6257 days, 115 patients acquired a total of 135 NIs distributed as follows: 36.3\% bacteremia, 30.4\% ventilator-associated pneumonia (VAP), 18.5\% catheter-associated urinary tract infection, 7.4\% central-line infection, 5.9\% cutaneous infection, and 1.3\% meningitis. The incidence rate of NI was 21.6 in 1000 patient-days, and the rate of NI was 25.6\%. Length of ICU stay, central venous catheterisation, mechanical ventilation and tracheostomy were statistically significant risk factors for NI. Of all NI, 112 (83\%) were microbiologically-confirmed and 68.8\% of the isolates were Gram-negative, 27.6\% were Gram-positive, and 3.6\% were fungi. 23 (17\%) were clinically-defined infections. The most frequently isolated organism was P. aeruginosa (25\%), followed by S. aureus (21.4\%), E. coli (18.7\%) and A. baumannii (16.9\%). CONCLUSIONS: The bloodstream was the most common site and Gram-negatives were the most commonly reported causes of ICU infections.
This article was published in Med Sci Monit and referenced in Emergency Medicine: Open Access

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