alexa Nuclear receptor that identifies a novel retinoic acid response pathway.
Chemical Engineering

Chemical Engineering

Journal of Analytical & Bioanalytical Techniques

Author(s): Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM

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Abstract Molecular cloning and transcriptional activation studies have revealed a new protein similar to the steroid hormone receptors and which responds specifically to vitamin A metabolites. This protein is substantially different in primary structure and ligand specificity from the products of the previously described retinoic acid receptor gene family. By indicating the existence of an additional pathway through which retinoic acid may exert its effects, these data lead to a re-evaluation of retinoid physiology. This article was published in Nature and referenced in Journal of Analytical & Bioanalytical Techniques

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