alexa Occupational exposure to polyvinyl chloride as a risk factor for testicular cancer evaluated in a case-control study.


Journal of Clinical Toxicology

Author(s): Hardell L, Ohlson CG, Fredrikson M

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Abstract Occupational exposures were assessed in a case-control study on testicular cancer using self-administered questionnaires. In total, answers were obtained for 148 (91\%) cases and 315 (87\%) controls. Of the cases, 101 had seminoma and 47 had embryonal testicular cancer. An increased odds ratio (OR) was found for exposure to polyvinyl chloride (PVC) yielding an OR of 6.6 (95\% confidence interval, 1.4-32). The risk increased further if cases with self-reported cryptorchidism or orchitis were excluded. Six of the 7 exposed cases had seminoma. Exposure to other types of plastics did not significantly increase the risk of testicular cancer.
This article was published in Int J Cancer and referenced in Journal of Clinical Toxicology

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