Author(s): Magnin J, Masselot A, Menzel C, Colinge J
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Abstract We propose a new type of probabilistic scoring scheme framework for protein identification from peptide masses. We first introduce the framework itself and explain its requirements. In a second part, we describe a particular implementation and test it on a data set of more than 8000 MALDI-TOF spectra with known contents. Doing so, we also compare its performance to two widely used scoring schemes, thereby demonstrating the potential of the proposed approach.
This article was published in J Proteome Res
and referenced in Journal of Proteomics & Bioinformatics