Author(s): Salihu HM, Boos R, Schmidt W
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Abstract Between January 1989 and November 1996 we detected a total of 44 cases of anterior abdominal wall defects comprising 29 with an omphalocele and 15 with gastrochisis. The gestational age at antenatal diagnosis of gastrochisis (mean = 17 weeks, 95\% CI = 15-19) was significantly lower than for omphalocele (mean = 19.0 weeks, 95\% CI = 17-21). Whereas gastrochisis tended to occur in relatively younger mothers (mean age = 23 years), omphalocele was associated with a comparatively advanced maternal age (mean age = 28 years). The sensitivity of ultrasound detection was the same for both malformations (omphalocele = 86.2\%; gastrochisis = 86.7\%). Additional structural anomalies were found in a higher proportion of those with an omphalocele compared with those with gastrochisis (62\% vs. 20\%). All the three cases of chromosomal anomalies were detected in omphalocele fetuses with an intracorporeal liver. Perinatal mortality was higher, albeit nonsignificantly, among fetuses with omphalocele.
This article was published in J Obstet Gynaecol
and referenced in Journal of Neonatal Biology