alexa Optical coherence tomography patterns of stent restenosis.


Journal of Cardiovascular Diseases & Diagnosis

Author(s): Gonzalo N, Serruys PW, Okamura T, van Beusekom HM, GarciaGarcia HM,

Abstract Share this page

Abstract BACKGROUND: Stent restenosis is an infrequent but poorly understood clinical problem in the drug-eluting stent era. The aim of the study was to evaluate the morphologic characteristics of stent restenosis by optical coherence tomography (OCT). METHODS: Patients (n = 24, 25 vessels) presenting with angiographically documented stent restenosis were included. Quantitative OCT analysis consisted of lumen and stent area measurement and calculation of restenotic tissue area and burden. Qualitative restenotic tissue analysis included assessment of tissue structure, backscattering and symmetry, visible microvessels, lumen shape, and presence of intraluminal material. RESULTS: By angiography, restenosis was classified as diffuse, focal, and at the margins in 9, 11, and 5 vessels, respectively. By OCT, restenotic tissue structure was layered in 52\%, homogeneous in 28\%, and heterogeneous in 20\%. The predominant backscatter was high in 72\%. Microvessels were visible in 12\%. Lumen shape was irregular in 28\% and there was intraluminal material in 20\%. The mean restenotic tissue symmetry ratio was 0.58 +/- 0.19. Heterogeneous and low scattering restenotic tissue was more frequent in focal (45.5\% and 54.5\%, respectively) than in diffuse (0 and 11.1\%) and margin restenosis (0 and 0\%) (P = .005 for heterogeneous, P = .03 for low scattering). Restenosis patients with unstable angina symptoms presented more frequently irregular lumen shape (60 vs 6.7\%, P = .007). Stents implanted
  • DOI: 10.1016/j.ahj.2009.06.004
  • This article was published in Am Heart J and referenced in Journal of Cardiovascular Diseases & Diagnosis

    Relevant Expert PPTs

    Relevant Speaker PPTs

    Recommended Conferences

    • 19th Annual Cardiology Congress
      August 31-September 01, 2017 Philadelphia, USA
    • 23rd International Conference on Heart Diseases & Angiology
      Oct 16-17, 2017 Budapest, Hungary
    • 20th European Cardiology Congress
      October 16-18, 2017 Budapest, Hungary
    • 3rd Global Summit on Heart Diseases
      November 02-04, 2017 Bangkok, Thailand
    • 22nd World Cardiology Congress
      December 11-12, 2017 Rome, Italy

    Relevant Topics

    Peer Reviewed Journals
    Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
    International Conferences 2017-18
    Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

    Contact Us

    Agri, Food, Aqua and Veterinary Science Journals

    Dr. Krish

    1-702-714-7001 Extn: 9040

    Clinical and Biochemistry Journals

    Datta A

    1-702-714-7001Extn: 9037

    Business & Management Journals


    1-702-714-7001Extn: 9042

    Chemical Engineering and Chemistry Journals

    Gabriel Shaw

    1-702-714-7001 Extn: 9040

    Earth & Environmental Sciences

    Katie Wilson

    1-702-714-7001Extn: 9042

    Engineering Journals

    James Franklin

    1-702-714-7001Extn: 9042

    General Science and Health care Journals

    Andrea Jason

    1-702-714-7001Extn: 9043

    Genetics and Molecular Biology Journals

    Anna Melissa

    1-702-714-7001 Extn: 9006

    Immunology & Microbiology Journals

    David Gorantl

    1-702-714-7001Extn: 9014

    Informatics Journals

    Stephanie Skinner

    1-702-714-7001Extn: 9039

    Material Sciences Journals

    Rachle Green

    1-702-714-7001Extn: 9039

    Mathematics and Physics Journals

    Jim Willison

    1-702-714-7001 Extn: 9042

    Medical Journals

    Nimmi Anna

    1-702-714-7001 Extn: 9038

    Neuroscience & Psychology Journals

    Nathan T

    1-702-714-7001Extn: 9041

    Pharmaceutical Sciences Journals

    John Behannon

    1-702-714-7001Extn: 9007

    Social & Political Science Journals

    Steve Harry

    1-702-714-7001 Extn: 9042

    © 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version