alexa Optical torques guiding cell motility.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Computer Science & Systems Biology

Author(s): Biener G, Vrotsos E, Sugaya K, Dogariu A

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Abstract The main mechanism responsible for cell motility is the stochastic generation and breakup of actin filaments forming the cytoskeleton. However, the role of environmental factors in the migration and differentiation of cells is yet to be fully understood. Here we demonstrate that polarized optical fields can exert controllable torques on the actin network and therefore influence the treadmilling process responsible for cells motility. Through systematic experiments and stochastic modeling we demonstrate that actively guiding the dynamics of large groups of cells is possible in a noninvasive manner.
This article was published in Opt Express and referenced in Journal of Computer Science & Systems Biology

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