Author(s): Helmerson K, Kishore R, Phillips WD, Weetall HH
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Abstract We used optical tweezers (optical trapping technology) to measure the force required to separate antigen-antibody bonds. Under competitive-binding conditions, we used the force determination to detect and measure protein antigen concentrations as small as 1 fmol/L (10(-15) mol/L).
This article was published in Clin Chem
and referenced in Arts and Social Sciences Journal