alexa Optimizing outcomes with maximal surgical resection of malignant gliomas.


Journal of Brain Tumors & Neurooncology

Author(s): Hentschel SJ, Sawaya R

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Abstract BACKGROUND: Aggressive surgical resection of malignant gliomas is a controversial issue in neurosurgery. Studies with rigorous methodology that fully address this issue have only recently become available. METHODS: The controversy regarding the role of maximal surgical resection of malignant gliomas is reviewed. The authors discuss surgical techniques and adjunctive technologies that can be utilized to assist in resection of these lesions. RESULTS: Using current microneurosurgical techniques, it is possible to resect malignant gliomas in gross total fashion. An aggressive approach in which 98\% or more of the tumor mass is resected results in a statistically significant survival advantage. CONCLUSIONS: An aggressive surgical procedure for malignant gliomas can result in increased survival duration for selected groups of patients.
This article was published in Cancer Control and referenced in Journal of Brain Tumors & Neurooncology

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