alexa Orbital Pseudotumor: Uncommon Initial Presentation of IgG4-Related Disease.
Immunology

Immunology

Rheumatology: Current Research

Author(s): Carbone T, Azdo Montes R, Andrade B, Lanzieri P, Mocarzel L

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Abstract IgG4-related disease (IgG4-RD) encompasses a group of fibroinflammatory conditions recognized in recent times. The main clinical features include variable degrees of tissue fibrosis, tumorlike expansions, perivascular lymphocytic infiltration rich in IgG4-positive plasma cells, and elevated serum IgG4. A case has been reported of an elderly patient with an unexplained unilateral exophthalmia; biopsy was performed and revealed lymphocytic infiltration, suggesting IgG4-RD. High serum levels of IgG4, in association with a good response to steroid therapy and to the exclusion of other diagnoses, confirmed the hypothesis of orbital pseudotumor by IgG4-RD.
This article was published in Case Rep Rheumatol and referenced in Rheumatology: Current Research

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