Author(s): Saxena MC, Siddiqui MK, Seth TD, Krishna Murti CR, Bhargava AK,
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Abstract Organochlorine insecticides (BHC, aldrin, p,p'-DDE, p,p'-DDD, p,p'-DDT) were measured in the blood, placenta and fetus of women experiencing spontaneous abortions, preterm labor or full-term labor using an electron-capture gas chromatographic method. The following trend was found for insecticide concentrations in each of the specimens tested: spontaneous abortions greater than preterm greater than full-term. One conclusion of this work is that the organochlorine insecticides act as antagonists to pregnancy. A plausible explanation for the facilitory role of organochlorine insecticides in the initiation of preterm labor/abortion is hypothesized.
This article was published in J Anal Toxicol
and referenced in Reproductive System & Sexual Disorders: Current Research