alexa Osteonecrosis of the hip in sickle-cell disease associated with tuberculous arthritis. A review of 15 cases.
Pharmaceutical Sciences

Pharmaceutical Sciences

Clinical Pharmacology & Biopharmaceutics

Author(s): Varango G, Bamba I, Kodo M, Dao A, Lambin Y

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Abstract We report a study of 15 cases of tuberculous hips with sickle-cell disease who presented during 1991-1993. Although the osteonecrosis was long-standing, biopsy was nearly always required to reveal the more recent tuberculous infection. Management consisted of 6 months of anti-tuberculous chemotherapy with appropriate palliative surgery 5-8 weeks after the start of drug treatment. The operative techniques which we used are described. The results were good both post-operatively, and in 12 patients followed-up at an average of 3 years. We recommend this combined management for the treatment of secondary tuberculous infections of hips previously damaged by sickle-cell disease.
This article was published in Int Orthop and referenced in Clinical Pharmacology & Biopharmaceutics

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