alexa Ozone and cause-specific cardiorespiratory morbidity and mortality.


Journal of Pulmonary & Respiratory Medicine

Author(s): Halonen JI, Lanki T, Tiittanen P, Niemi JV, Loh M,

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Abstract BACKGROUND: Health effects of ozone have been observed in numerous studies. However, analyses of more cause-specific morbidity or mortality outcomes have rarely been performed. A study was undertaken to determine the short-term associations of ozone with cause-specific cardiorespiratory mortality and morbidity by age groups. METHODS: Daily levels of ozone were measured at a background measurement station in 1998-2004 in Helsinki, Finland. All analyses were a priori restricted to the warm season. Daily cause-specific cardiorespiratory mortality and hospital admissions were studied in elderly people (> or =65 years) and adults (15-64 years) and associations between ozone and asthma emergency room visits in children (<15 years) were analysed. All models were adjusted for PM(2.5) and Poisson regression was used for the analyses. RESULTS: There was a positive association between ozone and admissions for asthma-chronic obstructive pulmonary disease (COPD) in elderly people (9.6\%; 95\% CI 2.0\% to 17.8\% at 0-day lag for 25 microg/m(3) increase in ozone). Consistent associations were also found between ozone and asthma emergency room visits in children (12.6\%; 95\% CI 0.8\% to 25.1\%, 0-day lag). There was a suggestion of an association between ozone and admissions for arrhythmia among elderly people (6.4\%; 95\% CI 0.63\% to 12.5\%, 1-day lag), which was slightly confounded by PM(2.5). CONCLUSIONS: Positive associations were found for ambient ozone with asthma visits among children and with pooled asthma/COPD admissions among elderly people. The evidence for a positive association between ozone and cardiovascular health was weaker. This article was published in J Epidemiol Community Health and referenced in Journal of Pulmonary & Respiratory Medicine

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