alexa Parkinsonism and midbrain dysfunction after shunt placement for obstructive hydrocephalus.
Oncology

Oncology

Journal of Nuclear Medicine & Radiation Therapy

Author(s): Yomo S, Hongo K, Kuroyanagi T, Kobayashi S

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Abstract We report a patient in whom placement of a ventriculoperitoneal shunt for obstructive hydrocephalus secondary to non-neoplastic aqueductal stenosis was complicated by progressive parkinsonism and midbrain dysfunction. These sequelae were refractory to treatment, including shunt revision and levodopa therapy. These findings contradict the opinion from the literature that this type of parkinsonism is a reversible condition and levodopa therapy is effective for managing the symptoms. We discuss the pathophysiological mechanism of this complication. This article was published in J Clin Neurosci and referenced in Journal of Nuclear Medicine & Radiation Therapy

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