alexa Pathological Fractures in Primary Non-Hodgkin’s Lymphoma of the Bone: A Case Series with Review of the Literature


Journal of Orthopedic Oncology

Author(s): Yasir Salam Siddiqui

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Primary non-Hodgkin’s lymphoma of bone (PLB) is a rare entity. Patients generally present with localized bone pain and, less frequently, soft-tissue swelling or a palpable mass. Pathological fracture of the proximal femur and proximal humerus secondary to soft-tissue tumours is well documented in the literature; however, lymphomas presenting primarily at these sites with pathological fracture is unusual. A review of the world literature shows that the incidence of skeletal manifestation from NHL is less than 5%, and in all these cases, bony involvement was reported many years after presentation of the primary cancer. Histopathologically, PLB usually represents diffuse large B-cell lymphoma. We report our experience with two cases of Primary non-Hodgkin’s lymphoma of proximal femur and proximal humerus with pathological fracture and their management.

This article was published in J Clin Diagn Res and referenced in Journal of Orthopedic Oncology

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