alexa Pathology of equine granulomatous enteritis.


Mycobacterial Diseases

Author(s): Lindberg R

Abstract Share this page

Abstract A morphological study on equine granulomatous enteritis (EGE) in 13 horses is presented. All horses were young (1 to 5 years old) standardbreds. Based on gross pathology, cases were classified into those with diffuse (11 cases) and those with localized (2 cases) small bowel lesions. The granulomatous reaction in the gut was marked by diffuse and patchy infiltrates and distinct granulomas, composed of epithelioid cells, macrophages and lymphoid cells, and was devoid of necrosis. Salient accompanying features of the small bowel included lymphoid hyperplasia, peri-lymphatic and transmural inflammation, lymphangiectasia, villous atrophy, mucosal ulcerations and crypt abscesses. Granulomatous changes were often demonstrated in alimentary tract tissues beyond the small bowel and its lymph nodes and were in some cases shown to occur multi-systemically. The morphology and epidemiological features of the condition suggest a specific aetiology. The histology indicated that an immune reaction was operative and that inflammation of the lamina propria was an early event in the pathogenesis of the gut lesion. No conclusive evidence of a specific infectious cause was found. It is suggested that the disease might be associated with intrinsic disturbances of inflammatory defence mechanisms.
This article was published in J Comp Pathol and referenced in Mycobacterial Diseases

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version