alexa Patterns, predictors and impact of substance use in early psychosis: a longitudinal study.


Journal of Addiction Research & Therapy

Author(s): Addington J, Addington D

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Abstract OBJECTIVE: The purpose was to determine the prevalence of substance use and its impact on outcome 3 years after presentation for a first-episode of psychosis. METHOD: Subjects were 203 consecutive admissions to an early psychosis program. Assessments included substance use, positive, negative and depressive symptoms and social functioning. Assessments occurred at baseline, and 1-, 2- and 3-year follow-ups. RESULTS: The prevalence of substance misuse was high with 51\% having a substance use disorder (SUD), 33\% with cannabis SUD and 35\% with an alcohol SUD. Numbers with an alcohol SUD declined considerably by 1 year and for cannabis SUD by 2 years. Substance misuse was significantly associated with male gender, young age and age of onset and cannabis misuse with increased positive symptoms. CONCLUSION: This study confirms the high rates of substance misuse, in particular cannabis, in first-episode psychosis. It further demonstrates that these rates can be reduced. This article was published in Acta Psychiatr Scand and referenced in Journal of Addiction Research & Therapy

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