alexa Percutaneous collagen induction versus full-concentration trichloroacetic acid in the treatment of atrophic acne scars.
Dermatology

Dermatology

Journal of Clinical & Experimental Dermatology Research

Author(s): Leheta T, El Tawdy A, Abdel Hay R, Farid S

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Abstract BACKGROUND: Percutaneous collagen induction (PCI) promotes removal of damaged collagen and induces more collagen immediately under the epidermis. The chemical reconstruction of skin scars (CROSS) method is a focal application of full-concentration trichloroacetic acid (TCA) to atrophic acne scars. The CROSS method has the advantage of reconstructing acne scars by increasing dermal thickening and collagen production. OBJECTIVE: To compare the safety and efficacy of PCI and the 100\% TCA CROSS method for the treatment of atrophic acne scars. MATERIALS AND METHODS: Thirty participants were randomly equally divided into two groups; group 1 underwent four sessions (4 weeks apart) of PCI, and group 2 underwent four sessions (4 weeks apart) of 100\% TCA CROSS. RESULTS: Acne scarring improved in 100\% of patients. Scar severity scores improved by a mean of 68.3\% (p<.001) in group 1 and a mean of 75.3\% (p<.001) in group 2. The difference in the degree of improvement was not statistically significant between the groups (p=.47). CONCLUSIONS: PCI and 100\% TCA CROSS were effective in the treatment of atrophic acne scars. © 2011 by the American Society for Dermatologic Surgery, Inc. This article was published in Dermatol Surg and referenced in Journal of Clinical & Experimental Dermatology Research

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